Karen Adelman has pioneered research into the pausing of RNA polymerase II during early transcription elongation and the impact of this regulation on gene networks involved in development and immune responses. She received her Ph.D. from the Université de Paris VI, doing research at the Institut Pasteur as a National Science Foundation Pre-doctoral Fellow, and carried out post-doctoral research at Cornell University. Since 2005, she has been an investigator at the National Institutes of Health, working in the National Institute of Environmental Health Sciences (NIEHS). Her laboratory uses genomic, genetic and biochemical techniques to investigate signal-dependent gene regulation in Drosophila and mammalian systems, focusing on the interplay between transcription activity and epigenetic features of promoter and enhancer regions.
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